Article
Progress towards completing the mutant mouse null resource.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2022
Peterson Kevin A, Murray Stephen A
Abstract excerpt
The generation of a comprehensive catalog of null alleles covering all protein-coding genes is the goal of the International Mouse Phenotyping Consortium. Over the past 20 years, significant progress has been made towards achieving this goal through the combined efforts of many large-scale programs that built an embryonic stem cell resource to generate knockout mice and more recently employed CRISPR/Cas9-based...
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