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Article

An exploratory study to evaluate efficacy and safety of frequent Transcutaneous Electrical Stimulation for Leber Hereditary Optic Neuropathy.

Scientific reports - 9 Feb 2025

Takano Fumio, Ueda Kaori, Kurimoto Takuji, Arai Mina, Nagai Takayuki, Yamada-Nakanishi Yuko, Nakamura Makoto

Abstract excerpt

Electrical stimulation (ES) may be effective for intractable retinal or optic nerve diseases. We studied frequent transcutaneous ES in a single-center, single-arm prospective study in patients with Leber hereditary optic neuropathy (LHON) who carry the mitochondrial (mt) 11778 G > A mutation. A 30-min ES was applied to either eye every other day for 12 weeks. The primary outcome was the difference in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39924552
DOI: 10.1038/s41598-025-89076-z
PMCID: PMC11808102

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