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Mesenchymal stem cells (MSCs) in Leber's hereditary optic neuropathy (LHON): a potential therapeutic approach for future.

International ophthalmology - 1 Sept 2022

Subramaniam Mohana Devi, Chirayath Ruth Bright, Iyer Mahalaxmi, Nair Aswathy P, Vellingiri Balachandar

Abstract excerpt

BACKGROUND: Optic neuropathy has become a new typical syndromic multi-system disease that leads to optic atrophy. This review discusses potential treatments and advances of Leber's hereditary optic neuropathy (LHON), a sporadic genetic disorder. LHON is caused due to slight mutations in mitochondria leading to mitochondrial dysfunction, causing vision loss. There are no current significant treatments that have...

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Adenosine Triphosphate
DNA, Mitochondrial
Mesenchymal Stem Cells
Mitochondria
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Optic Atrophy, Hereditary, Leber

Reactive Oxygen Species

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PMID: 35357640
DOI: 10.1007/s10792-022-02267-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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