Article
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation.
Mitochondrion - 1 May 2023
Miao Qingmei, Cheng Yufang, Zheng Hongmei, Yuan Jiajia, Chen Changzheng
Abstract excerpt
PURPOSE: To analyze the functional and structural changes in retinal ganglion cells (RGCs) and their axons that occur during Leber's hereditary optic neuropathy (LHON) using photopic negative response (PhNR) and spectral domain optical coherence tomography (SD-OCT). METHODS: Individuals diagnosed with LHON and their family members were invited to participate in this cross-sectional study. PhNR and OCT were used....
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