Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.

Frontiers in endocrinology - 1 Jan 2024

Chen Peng, Wei Xin, Li Xiao-Ke, Zhou Yi-Hang, Liu Qi-Fang, Ou-Yang Ling

Abstract excerpt

Introduction: Endometriosis (EM) is a widely recognized disorder in gynecological endocrinology. Although hormonal therapies are frequently employed for EM, their side effects and outcome limitations underscore the need to explore the genetic basis and potential drug targets for developing innovative therapeutic approaches. This study aimed to identify both cerebrospinal fluid (CSF) and plasma protein markers as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Endometriosis
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Protein Interaction Maps

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 39911230
DOI: 10.3389/fendo.2024.1371498
PMCID: PMC11794050

Genes

RSPO3
CPE
FN1
FUT5
LGALS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.PMID 39911230Read ↗

Mendelian randomization Identifies RSPO3 in Serum as a Potential Target for EndometriosisSemantic proximity Read ↗

The effects of plasma protein levels on the risk of endometriosis: A Mendelian randomization study.Semantic proximity Read ↗

Prioritization of potential drug targets in ovarian-related diseases: Mendelian randomization and colocalization analyses.Semantic proximity Read ↗

Bioinformatics identification and validation of biomarkers and infiltrating immune cells in endometriosisSemantic proximity Read ↗

Genetic variation perspective reveals potential drug targets for subtypes of endometrial cancer.Semantic proximity Read ↗

The Causal Relationship Between the Levels of 91 Circulating Inflammatory Proteins and Ovarian-Related Diseases: A Bidirectional Mendelian Randomization Study.Semantic proximity Read ↗

LGALS2 and EGR1: markers of endometriosis for predictive, preventive and personalized medicineSemantic proximity Read ↗

Non-targeted metabolomics revealed novel links between serum metabolites and primary ovarian insufficiency: a Mendelian randomization study.Semantic proximity Read ↗

Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosteroneSemantic proximity Read ↗

Unraveling shared diagnostic genes and cellular microenvironmental changes in endometriosis and recurrent implantation failure through multi-omics analysisSemantic proximity Read ↗

Proteome-wide Mendelian randomization and functional studies uncover therapeutic targets for polycystic ovarian syndrome.Semantic proximity Read ↗

Genetic Contribution of Endometriosis to the Risk of Developing Hormone-Related Cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.