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Article

Fine-tuning GBS data with comparison of reference and mock genome approaches for advancing genomic selection in less studied farmed species.

BMC genomics - 5 Feb 2025

Fischer Daniel, Tapio Miika, Bitz Oliver, Iso-Touru Terhi, Kause Antti, Tapio Ilma

Abstract excerpt

BACKGROUND: Diversifying animal cultivation demands efficient genotyping for enabling genomic selection, but non-model species lack efficient genotyping solutions. The aim of this study was to optimize a genotyping-by-sequencing (GBS) double-digest RAD-sequencing (ddRAD) pipeline. Bovine data was used to automate the bioinformatic analysis. The application of the optimization was demonstrated on non-model...

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Topics

Animals
Cattle
Genomics
Genome
Genotyping Techniques
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Sequence Analysis, DNA

Computational Biology

Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 39910437
DOI: 10.1186/s12864-025-11296-4
PMCID: PMC11796084

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