Article
Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis).
BMC genomics - 20 May 2015
Miller Joshua M, Moore Stephen S, Stothard Paul, Liao Xiaoping, Coltman David W
Abstract excerpt
BACKGROUND: Whole genome sequences (WGS) have proliferated as sequencing technology continues to improve and costs decline. While many WGS of model or domestic organisms have been produced, a growing number of non-model species are also being sequenced. In the absence of a reference, construction of a genome sequence necessitates de novo assembly which may be beyond the ability of many labs due to the large...
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