Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential resistance to nematode infection is associated with the genotype- and age-dependent pace of intestinal T cell homing.

Scientific reports - 5 Feb 2025

Adjah Joshua, Kapse Bhavya, Zhang Hongwei, Hartmann Susanne, Rausch Sebastian

Abstract excerpt

The resistance of inbred mice to nematode infections varies depending on the extent of protective Th2 responses. Here, we compared two mouse lines differing in resistance to infection with the enteric nematode Heligmosomoides polygyrus bakeri despite the similar instruction of GATA-3+ T effector cells. Resistant BALB/c mice rapidly recruited high numbers of Th2 cells to the gut within the 1-week time frame...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Resistance

Share to GATA3 Transcription Factor

Share to Intestinal Mucosa

Share to Mice, Inbred BALB C

Share to Strongylida Infections

Share to Th2 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 39910093
DOI: 10.1038/s41598-024-76204-4
PMCID: PMC11799532

Genes

CCR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential resistance to nematode infection is associated with the genotype- and age-dependent pace of intestinal T cell homing.PMID 39910093Read ↗

Genetic variation in resistance to repeated infections with Heligmosomoides polygyrus bakeri, in inbred mouse strains selected for the mouse genome project.Semantic proximity Read ↗

Elucidating different pattern of immunoregulation in BALB/c and C57BL/6 mice and their F1 progeny.Semantic proximity Read ↗

Cutting edge: in the absence of TGF-β signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-γ production renders mice more susceptible to helminth infection.Semantic proximity Read ↗

The relative involvement of Th1 and Th2 associated immune responses in the expulsion of a primary infection of Heligmosomoides polygyrus in mice of differing response phenotype.Semantic proximity Read ↗

Systemic dissemination and persistence of Th2 and type 2 cells in response to infection with a strictly enteric nematode parasite.Semantic proximity Read ↗

A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective ImmunitySemantic proximity Read ↗

Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice.Semantic proximity Read ↗

Immune modulation and modulators in Heligmosomoides polygyrus infection.Semantic proximity Read ↗

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus.Semantic proximity Read ↗

Inbred SJL mice recapitulate human resistance to Cryptococcus infection due to differential immune activationSemantic proximity Read ↗

T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavitySemantic proximity Read ↗

Genetic background influences immune responses and disease outcome of cutaneous L. mexicana infection in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.