Article
Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus.
Seminars in immunopathology - 1 Nov 2012
Reynolds Lisa A, Filbey Kara J, Maizels Rick M
Abstract excerpt
Heligmosomoides polygyrus is a natural intestinal parasite of mice, which offers an excellent model of the immunology of gastrointestinal helminth infections of humans and livestock. It is able to establish long-term chronic infections in many strains of mice, exerting potent immunomodulatory effects that dampen both protective immunity and bystander reactions to allergens and autoantigens. Immunity to the...
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