Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune modulation and modulators in Heligmosomoides polygyrus infection.

Experimental parasitology - 1 Sept 2012

Maizels Rick M, Hewitson James P, Murray Janice, Harcus Yvonne M, Dayer Blaise, Filbey Kara J, Grainger John R, McSorley Henry J, Reynolds Lisa A, Smith Katherine A

Abstract excerpt

The intestinal nematode parasite Heligmosomoides polygyrus bakeri exerts widespread immunomodulatory effects on both the innate and adaptive immune system of the host. Infected mice adopt an immunoregulated phenotype, with abated allergic and autoimmune reactions. At the cellular level, infection is accompanied by expanded regulatory T cell populations, skewed dendritic cell and macrophage phenotypes, B cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptive Immunity
Share to Antibody Specificity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antigens, Helminth

Share to Dendritic Cells

Share to Immunomodulation

Share to Strongylida Infections

Share to T-Lymphocyte Subsets

Share to T-Lymphocytes, Regulatory

Source

Open in PubMed Open full text

Identifiers

PMID: 21875581
DOI: 10.1016/j.exppara.2011.08.011
PMCID: PMC6485391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune modulation and modulators in Heligmosomoides polygyrus infection.PMID 21875581Read ↗

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus.Semantic proximity Read ↗

Systemic dissemination and persistence of Th2 and type 2 cells in response to infection with a strictly enteric nematode parasite.Semantic proximity Read ↗

Cutting edge: in the absence of TGF-β signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-γ production renders mice more susceptible to helminth infection.Semantic proximity Read ↗

Cytokines from parasites: manipulating host responses by molecular mimicrySemantic proximity Read ↗

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode InfectionSemantic proximity Read ↗

The relative involvement of Th1 and Th2 associated immune responses in the expulsion of a primary infection of Heligmosomoides polygyrus in mice of differing response phenotype.Semantic proximity Read ↗

Genetic and immunological adaptation of Heligmosomoides polygyrus in mice.Semantic proximity Read ↗

A helminth-derived suppressor of ST2 blocks allergic responsesSemantic proximity Read ↗

Antigens in phenotypes of Heligmosomoides polygyrus raised selectively from different strains of mice.Semantic proximity Read ↗

Microbial regulation of enteric eosinophils and its impact on tissue remodeling and Th2 immunitySemantic proximity Read ↗

Cellular and serological responses in resistant and susceptible mice exposed to repeated infection with Heligmosomoides polygyrus bakeri.Semantic proximity Read ↗

Coevolutionary interplay: Helminths-trained immunity and its impact on the rise of inflammatory diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.