Article
Consomic rat model systems for physiological genomics.
Acta physiologica Scandinavica - 1 Aug 2004
Cowley A W, Liang M, Roman R J, Greene A S, Jacob H J
Abstract excerpt
A consomic rat strain is one in which an entire chromosome is introgressed into the isogenic background of another inbred strain using marker-assisted selection. The development and physiological screening of two inbred consomic rat panels on two genetic backgrounds (44 strains) is well underway. Consomic strains enable one to assign traits and quantitative trait loci (QTL) to chromosomes by surveying the panel...
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