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mRNA-LM: full-length integrated SLM for mRNA analysis

20 Jan 2025

Abstract excerpt

The success of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) messenger RNA (mRNA) vaccine has led to increased interest in the design and use of mRNA for vaccines and therapeutics. Still, selecting the most appropriate mRNA sequence for a protein remains a challenge. Several recent studies have shown that the specific mRNA sequence can have a significant impact on the translation efficiency,...

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PMID: 39898548
DOI: 10.1093/nar/gkaf044

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