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Article

Genetic Variants of GBP4: Reduced Risks for Drug-Induced Acute Liver Failure in Non-Finnish European Population.

Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2025

Liao Tsung-Jen, Xia Menghang, Hayashi Paul, Pan Bohun, Aithal Guruprasad P, Lucena M Isabel, Andrade Raúl J, Rule Jody A, Lee William M, Rakela Jorge, Huang Ruili, Chen Minjun

Abstract excerpt

BACKGROUND AND AIMS: Acute liver failure (ALF) is a serious condition, typically in individuals without prior liver disease. Drug-induced ALF (DIALF) constitutes a major portion of ALF cases. Our research aimed to identify potential genetic predispositions to DIALF. METHODS: We analysed the potential genetic variants associated with DIALF using the whole exome sequencing data from 75 cases, including 40...

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Identifiers

PMID: 39868816
DOI: 10.1111/liv.70011
PMCID: PMC11850085

Genes

GBP4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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