Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SNP rs9364554 Modulates Androgen Receptor Binding and Drug Response in Prostate Cancer.

Biomolecules - 4 Jan 2025

Yan Yuqian, Shi Lei, Ma Tao, Wang Liguo, Huang Haojie

Abstract excerpt

(1) Background: Prostate cancer treatment efficacy is significantly influenced by androgen receptor (AR) signaling pathways. SLC22A3, a membrane transporter, has been linked to SNP rs9364554 risk loci for drug efficacy in prostate cancer. (2) Methods: We examined the location of SNP rs9364554 in the genome and utilized TCGA and other publicly available datasets to analyze the association of this SNP with SLC22A3...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Drug Resistance, Neoplasm

Share to Gene Expression Regulation, Neoplastic

Share to Hepatocyte Nuclear Factor 3-alpha

Share to Organic Cation Transport Proteins

Share to Promoter Regions, Genetic

Share to Prostatic Neoplasms

Share to Receptors, Androgen

Source

Open in PubMed Open full text

Identifiers

PMID: 39858458
DOI: 10.3390/biom15010064
PMCID: PMC11763896

Genes

SLC22A3
AR
FOXA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SNP rs9364554 Modulates Androgen Receptor Binding and Drug Response in Prostate Cancer.PMID 39858458Read ↗

SLCO1B3 and SLCO2B1 genotypes, androgen deprivation therapy, and prostate cancer outcomes: a prospective cohort study and meta-analysis.Semantic proximity Read ↗

Integrative genomic and bioinformatic prioritization of drug repurposing candidates for prostate cancer.Semantic proximity Read ↗

Abiraterone induces SLCO1B3 expression in prostate cancer via microRNA-579-3pSemantic proximity Read ↗

Polymorphisms of the androgen transporting gene SLCO2B1 may influence the castration resistance of prostate cancer and the racial differences in response to androgen deprivation.Semantic proximity Read ↗

Genome-wide association study identifies novel single nucleotide polymorphisms having age-specific effect on prostate-specific antigen levels.Semantic proximity Read ↗

Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer.Semantic proximity Read ↗

A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer.Semantic proximity Read ↗

HSD3B1 variant and androgen-deprivation therapy outcome in prostate cancer.Semantic proximity Read ↗

Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgen-insensitive prostate cancer cell invasion.Semantic proximity Read ↗

Search for genetic factor association with cancer-free prostate-specific antigen level elevation on the basis of a genome-wide association study in the Korean population.Semantic proximity Read ↗

SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.Semantic proximity Read ↗

Cav1.3 channel α1D protein is overexpressed and modulates androgen receptor transactivation in prostate cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.