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Associations and potential epigenetic changes between air pollution and osteoarthritis risk and survival: Insights from a prospective cohort study

1 Jan 2025

Abstract excerpt

BACKGROUND: The influence of air pollution on osteoarthritis (OA) remains underexplored. METHODS: ), and air pollutants exposure score (APES). Cox models assessed associations between air pollution exposure and OA incidence, joint replacement, and survival. Additionally, using genome-wide association statistics, we examined the potential causal associations between air pollution-related DNA methylation (DNAm) and...

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PMID: 39847883
DOI: 10.1016/j.ecoenv.2025.117770

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