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Air pollution, genetic factors, and chronic rhinosinusitis: A prospective study in the UK Biobank.

The Science of the total environment - 25 Aug 2024

Zhou Qinfeng, Ma Junxiong, Biswal Shyam, Rowan Nicholas R, London Nyall R, Riley Charles A, Lee Stella E, Pinto Jayant M, Ahmed Omar G, Su Mintao, Liang Zhisheng, Du Runming, Ramanathan Murugappan, Zhang Zhenyu

Abstract excerpt

BACKGROUND: Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition that manifests in two primary subtypes: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). While previous studies indicate a correlation between air pollution and CRS, the role of genetic predisposition in this relationship remains largely unexplored. We hypothesized that higher air pollution exposure would lead...

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PMID: 38825199
DOI: 10.1016/j.scitotenv.2024.173526

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