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Article

Causal relationship between genetically predicted uterine leiomyoma and cancer risk: a two-sample Mendelian randomization.

Frontiers in endocrinology - 1 Jan 2024

Zhao Chenyang, Shang Anquan, Wu Han, Li Qiong, Peng Lixiu, Yue Chaoyan

Abstract excerpt

Purpose: Studies have demonstrated that hormonal imbalance, such as elevated level of estrogen or reduced level of progesterone, was the main inducing factor of uterine leiomyoma (UL) development and some cancers. UL has been reported to be associated with several cancers in observational studies. However, the causal associations between UL and cancers remain unclear. Methods: A two-sample Mendelian randomization...

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Share to Endometrial and Cervical Cancer Treatments
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 39268242
DOI: 10.3389/fendo.2024.1429165
PMCID: PMC11390398

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