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Article

Resolution of oncogene-induced senescence markers in HPV-infected cervical cancer tissue

21 Jan 2025

Abstract excerpt

BACKGROUND: Oncogene-Induced Senescence (OIS) is a form of senescence that occurs as a consequence of oncogenic overstimulation and possibly infection by oncogenic viruses. Whether senescence plays a role in the pathogenesis of cervical cancer (CC) is not well understood. Moreover, whether cervical epithelial cells that are part of the premalignant cervical intraepithelial neoplasia (CIN), exhibit markers of OIS...

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PMID: 39838347
DOI: 10.1186/s12885-025-13499-0

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