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Article

Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy

1 May 2021

Abstract excerpt

Senescence is a cell stress response induced by replicative, oxidative, oncogenic, and genotoxic stresses. Tumor cells undergo senescence in response to several cancer therapeutics in vitro (Therapy-Induced Senescence, TIS), including agents utilized as neoadjuvant chemotherapy (NAC) in the treatment of invasive breast cancer. TIS has been proposed to contribute to adverse therapy outcomes including relapse....

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Share to Advanced biosensing and bioanalysis techniques
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Share to Telomeres, Telomerase, and Senescence

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PMID: 33948615
DOI: 10.1042/bsr20210079

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