Myeloid dendritic cells and periodontal disease association: integrated study of single-cell sequencing and Mendelian randomization analysis.

Abstract excerpt

Background: Periodontal disease is a widespread inflammatory condition that compromises the supporting structures of the teeth, potentially resulting in tooth loss if left untreated. Despite advancements in therapeutic interventions and an enhanced understanding of its pathophysiology, emerging techniques such as single-cell RNA sequencing (scRNA-seq) and Mendelian randomization (MR) present new opportunities for...

Topics

• Humans
• Periodontal Diseases
• Mendelian Randomization Analysis
• Single-Cell Analysis
• Dendritic Cells
• Quantitative Trait Loci