Article

Single-cell Transcriptional Analysis of the Cellular Immune Response in the Oral Mucosa of Mice

2023-10-20

Abstract excerpt

Periodontal health is dependent on a symbiotic relationship of the host immune response with the oral microbiota. Pathologic shifts of the microbial plaque elicit an immune response that eventually leads to the recruitment and activation of osteoclasts and matrix metalloproteinases and the eventual tissue destruction that is evident in periodontal disease. Once the microbial stimulus is removed, an active process...

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Literature Corpus work: e7245e02-2d5c-5139-8325-ccb86852d481
DOI: 10.1101/2023.10.18.562816

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