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Article

Causal role of immune cells in chronic periodontitis: a bidirectional Mendelian randomization study.

BMC oral health - 16 Jul 2024

Chen Yu, Jin Xinyang, Wang Qi, Hu Sai, Huang Xu

Abstract excerpt

BACKGROUND: This study aims to explore the bidirectional causal relationship between immune cell phenotypes and chronic periodontitis using a Mendelian randomization framework. MATERIALS AND METHODS: Through a two-sample Mendelian randomization analysis, this research examined genetic data related to 731 immune cell traits and chronic periodontitis. Instrumental variables were chosen based on their genetic links...

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PMID: 39014403
DOI: 10.1186/s12903-024-04592-0
PMCID: PMC11253491

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