Article

Single-cell RNA-seq combined with bulk RNA-seq analysis identifies necroptosis-related genes as therapeutic targets for periodontitis

2025-05-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Necroptosis, a regulated form of cell self-destruction, exacerbates inflammatory responses by releasing damage-associated molecular patterns and inflammatory factors. However, the specific mechanisms underlying necroptosis in periodontitis remain poorly explored. This study integrated single-cell RNA sequencing (scRNA-seq) and transcriptome RNA sequencing (RNA-se...

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Literature Corpus work: 402625e0-43c1-585e-9594-91ddb61d2558
DOI: 10.21203/rs.3.rs-6576613/v1

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