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Article

Identification of cis-sQTL demonstrates genetic associations and functional implications of inflammatory processes in Nelore cattle muscle tissue.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2025

Dos Santos Thaís Cristina Ferreira, Silva Evandro Neves, Frezarim Gabriela Bonfá, Salatta Bruna Maria, Baldi Fernando, Fonseca Larissa Fernanda Simielli, Albuquerque Lucia Galvão De, Muniz Maria Malane Magalhães, Silva Danielly Beraldo Dos Santos

Abstract excerpt

This study aimed to identify splicing quantitative trait loci (cis-sQTL) in Nelore cattle muscle tissue and explore the involvement of spliced genes (sGenes) in immune system-related biological processes. Genotypic data from 80 intact male Nelore cattle were obtained using SNP-Chip technology, while RNA-Seq analysis was performed to measure gene expression levels, enabling the integration of genomic and...

Read the complete abstract on PubMed

Topics

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Share to Cattle
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Inflammation

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

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Source

Identifiers

PMID: 39825903
DOI: 10.1007/s00335-024-10100-0

Genes

TREM2
CASP1
CASP4
CASP6
GSDMA
GZMA
NAIP
NFKBIB
NLRP1
NLRP6
OPTN
PIDD1
STAT1
TNIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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