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Article

Novel putative causal mutations associated with fat traits in Nellore cattle uncovered by eQTLs located in open chromatin regions.

Scientific reports - 2 May 2024

Garcia Ingrid Soares, Silva-Vignato Bárbara, Cesar Aline Silva Mello, Petrini Juliana, da Silva Vinicius Henrique, Morosini Natália Silva, Goes Carolina Purcell, Afonso Juliana, da Silva Thaís Ribeiro, Lima Beatriz Delcarme, Clemente Luan Gaspar, Regitano Luciana Correia de Almeida, Mourão Gerson Barreto, Coutinho Luiz Lehmann

Abstract excerpt

Intramuscular fat (IMF) and backfat thickness (BFT) are critical economic traits impacting meat quality. However, the genetic variants controlling these traits need to be better understood. To advance knowledge in this area, we integrated RNA-seq and single nucleotide polymorphisms (SNPs) identified in genomic and transcriptomic data to generate a linkage disequilibrium filtered panel of 553,581 variants....

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Adipose Tissue
Cattle
Chromatin
Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Linkage Disequilibrium

Lipid Metabolism

Quantitative Trait Loci

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Identifiers

PMID: 38698200
DOI: 10.1038/s41598-024-60703-5
PMCID: PMC11066111

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