Exploring SNP filtering strategies: the influence of strict vs soft core.

Abstract excerpt

Phylogenetic analyses are crucial for understanding microbial evolution and infectious disease transmission. Bacterial phylogenies are often inferred from SNP alignments, with SNPs as the fundamental signal within these data. SNP alignments can be reduced to a 'strict core' by removing those sites that do not have data present in every sample. However, as sample size and genome diversity increase, a strict core...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genome, Bacterial
• Share to Neisseria gonorrhoeae