Optimally recovering rate variation information from genomes and sequences: pattern filtering.

doi:10.1093/oxfordjournals.molbev.a026030

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Article

Optimally recovering rate variation information from genomes and sequences: pattern filtering.

Molecular biology and evolution - 1 Sept 1998

Lake J A

Abstract excerpt

Nucleotide substitution rates vary at different positions within genes and genomes, but rates are difficult to estimate, because they are masked by the stochastic nature of substitutions. In this paper, a linear method, pattern filtering, is described which can optimally separate the signals (rel...

Topics

DNA, Mitochondrial
Fourier Analysis
Genetic Variation
Genome
Phylogeny

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