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Article

A Comprehensive Analysis of Sex-Biased Gene Expression in the Aging Human Retina Through a Combination of Single-Cell and Bulk RNA Sequencing

13 Jan 2025

Abstract excerpt

Purpose: Previous studies have reported divergent sexual responses to aging; however, specific variations in gene expression between aging males and females and their potential association with age-related retinal diseases remain unclear. This study collected data from public databases and developed a comprehensive comparison of retina between aging females and males. Methods: Single-cell RNA (scRNA) and bulk RNA...

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PMID: 39804630
DOI: 10.1167/iovs.66.1.28

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