Article
A Very Low-Carbohydrate Program in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease and Phospholipase Domain-Containing Protein 3 Risk Genotype: Pre-Post Intervention Study.
JMIR formative research - 10 Jan 2025
Saslow Laura R, Krinock Jamie, O'Brien Alison, Raymond Kaitlyn, Bayandorian Hovig, Moskowitz Judith T, Daubenmier Jennifer, Oliveri Antonino, Marriott Deanna J, Griauzde Dina H, Speliotes Elizabeth K
Abstract excerpt
Background: Insulin resistance and the G allele of rs738409 interact to create a greater risk of metabolic dysfunction-associated steatotic liver disease. Objective: This study aims to confirm that one promising way to reduce insulin resistance is by following a very low-carbohydrate (VLC) dietary pattern. Methods: Adults with rs738409-GG or -CG with liver steatosis and elevated liver function tests, were taught...
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