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Article

PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease.

Journal of gastroenterology and hepatology - 1 Jan 2015

Shen Jiayun, Wong Grace Lai-Hung, Chan Henry Lik-Yuen, Chan Ruth Suk-Mei, Chan Hoi-Yun, Chu Winnie Chiu-Wing, Cheung Bernice Ho-Ki, Yeung David Ka-Wai, Li Liz Sin, Sea Mandy Man-Mei, Woo Jean, Wong Vincent Wai-Sun

Abstract excerpt

BACKGROUND AND AIM: Lifestyle modification is the cornerstone for the management of nonalcoholic fatty liver disease (NAFLD), and patatin-like phospholipase 3 (PNPLA3) is one of the most important genetic determinants of NAFLD. We aimed to investigate the effect of PNPLA3 gene polymorphism on the response to lifestyle modification in NAFLD patients. METHODS: This was a post-hoc analysis of a randomized controlled...

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Identifiers

PMID: 25040896
DOI: 10.1111/jgh.12656

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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