Article
Drug resistance in non-B subtype HIV-1: impact of HIV-1 reverse transcriptase inhibitors.
Viruses - 24 Sept 2014
Singh Kamalendra, Flores Jacqueline A, Kirby Karen A, Neogi Ujjwal, Sonnerborg Anders, Hachiya Atsuko, Das Kalyan, Arnold Eddy, McArthur Carole, Parniak Michael, Sarafianos Stefan G
Abstract excerpt
Human immunodeficiency virus (HIV) causes approximately 2.5 million new infections every year, and nearly 1.6 million patients succumb to HIV each year. Several factors, including cross-species transmission and error-prone replication have resulted in extraordinary genetic diversity of HIV groups. One of these groups, known as group M (main) contains nine subtypes (A-D, F-H and J-K) and causes ~95% of all HIV...
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