Article
In-depth analysis of HIV-1 drug resistance mutations in HIV-infected individuals failing first-line regimens in West and Central Africa.
AIDS (London, England) - 13 Nov 2016
Villabona-Arenas Christian Julian, Vidal Nicole, Guichet Emilande, Serrano Laetitia, Delaporte Eric, Gascuel Olivier, Peeters Martine
Abstract excerpt
OBJECTIVE: In resource-limited countries, antiretroviral therapy (ART) has been scaled up, but individual monitoring is still suboptimal. Here, we studied whether or not ART had an impact on the frequency and selection of drug resistance mutations (DRMs) under these settings. We also examined whether differences exist between HIV-1 genetic variants. DESIGN: A total of 3736 sequences from individuals failing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
