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MR-Guided Focused Ultrasound-Enhanced Liquid Biopsy (Sonobiopsy) for the Definitive Differentiation of True Progression from Pseudoprogression in Glioblastoma: A Prospective Phase II Clinical Trial

2026-07-16

Abstract excerpt

<title>Abstract</title> <p> Background Distinguishing true tumor progression (PD) from treatment-induced pseudoprogression (PsP) in glioblastoma (GBM) remains a critical imaging challenge. While liquid biopsy offers a potential non-invasive solution, its sensitivity in central nervous system malignancies is restricted by low biomarkers shedding across the blood-brain barrier (BBB). We evaluated the diagnostic e...

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Literature Corpus work: fe7a7184-7831-5df7-ad2d-9ee5b955741c
DOI: 10.21203/rs.3.rs-10264269/v1

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