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Article

The coming of age of liquid biopsy in neuro-oncology.

Brain : a journal of neurology - 3 Oct 2023

Berzero Giulia, Pieri Valentina, Mortini Pietro, Filippi Massimo, Finocchiaro Gaetano

Abstract excerpt

The clinical role of liquid biopsy in oncology is growing significantly. In gliomas and other brain tumours, targeted sequencing of cell-free DNA (cfDNA) from CSF may help differential diagnosis when surgery is not recommended and be more representative of tumour heterogeneity than surgical specimens, unveiling targetable genetic alterations. Given the invasive nature of lumbar puncture to obtain CSF, the...

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Identifiers

PMID: 37289981
DOI: 10.1093/brain/awad195
PMCID: PMC10545511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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