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A hitchhiker’s guide to cell-free DNA biology

11 Nov 2022

Abstract excerpt

Liquid biopsy provides a noninvasive window to the cancer genome and physiology. In particular, cell-free DNA (cfDNA) is a versatile analyte for guiding treatment, monitoring treatment response and resistance, tracking minimal residual disease, and detecting cancer earlier. Despite certain successes, brain cancer diagnosis is amongst those applications that has so far resisted clinical implementation. Recent...

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PMID: 36380865
DOI: 10.1093/noajnl/vdac066

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