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pTau217 in Admixed South American Populations: Implications for Alzheimer’s Disease Diagnosis in Brazil and Argentina

2025-12-12

Abstract excerpt

<title>Abstract</title> <p> Plasma pTau217 is a leading biomarker for Alzheimer’s disease (AD), but evidence from low- and middle-income countries (LMICs) remains limited. We evaluated its diagnostic performance in two memory-clinic cohorts from Brazil (Cog-Aging-Study, n = 353) and Argentina (GeNED.ar, n = 134), both genetically admixed. Using data-driven mixture modelling with single- and two-cut-off approache...

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Literature Corpus work
431a77f7-a4da-5588-964c-f0fae8de5df9
DOI
10.21203/rs.3.rs-8216169/v1
Open publication

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pTau217 in Admixed South American Populations: Implications for Alzheimer’s Disease Diagnosis in Brazil and ArgentinaDOI 10.21203/rs.3.rs-8216169/v1
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