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Plasma p‐tau231 and p‐tau217 inform on tau tangles aggregation in cognitively impaired individuals

3 Aug 2023

Abstract excerpt

Abstract INTRODUCTION Phosphorylated tau (p‐tau) biomarkers have been recently proposed to represent brain amyloid‐β (Aβ) pathology. Here, we evaluated the plasma biomarkers' contribution beyond the information provided by demographics (age and sex) to identify Aβ and tau pathologies in individuals segregated as cognitively unimpaired (CU) and impaired (CI). METHODS We assessed 138 CU and 87 CI with available...

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PMID: 37534889
DOI: 10.1002/alz.13393

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