Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of association between common polymorphisms associated with successful aging and longevity in the population of Sardinian Blue Zone.

Scientific reports - 28 Dec 2024

Errigo Alessandra, Dore Maria Pina, Mocci Giammarco, Pes Giovanni Mario

Abstract excerpt

More than two decades ago, in the central-eastern region of the Mediterranean island of Sardinia, a mountain area was identified where the population displays exceptional longevity, especially among men (the Longevity Blue Zone, LBZ). This community was thoroughly investigated to understand the underlying causes of the phenomenon. The present study analyzed 11 genetic markers previously associated with increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Aging, and Longevity in Model Organisms

Share to Genotype

Share to Longevity

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39730495
DOI: 10.1038/s41598-024-80497-w
PMCID: PMC11680967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between common polymorphisms associated with successful aging and longevity in the population of Sardinian Blue Zone.PMID 39730495Read ↗

Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.Semantic proximity Read ↗

No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.Semantic proximity Read ↗

A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals.Semantic proximity Read ↗

Genome-wide scan with nearly 700,000 SNPs in two Sardinian sub-populations suggests some regions as candidate targets for positive selection.Semantic proximity Read ↗

Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians.Semantic proximity Read ↗

Health status and 6 years survival of 552 90+ Italian sib-ships recruited within the EU Project GEHA (GEnetics of Healthy Ageing).Semantic proximity Read ↗

Commonly studied polymorphisms in inflammatory cytokine genes show only minor effects on mortality and related risk factors in nonagenarians.Semantic proximity Read ↗

Is the ACE I/D polymorphism associated with extreme longevity? A study on a Spanish cohort.Semantic proximity Read ↗

Ataxia-telangiectasia mutated (ATM) genetic variant in Italian centenarians.Semantic proximity Read ↗

Lack of association between polymorphisms in the SIRT6 gene and longevity in a Chinese population.Semantic proximity Read ↗

Associations between STR autosomal markers and longevity.Semantic proximity Read ↗

Lack of replication of genetic associations with human longevity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.