Article
No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
Experimental gerontology - 1 Jun 2016
Soerensen Mette, Nygaard Marianne, Debrabant Birgit, Mengel-From Jonas, Dato Serena, Thinggaard Mikael, Christensen Kaare, Christiansen Lene
Abstract excerpt
In this study we explored the association between aging-related phenotypes previously reported to predict survival in old age and variation in 77 genes from the DNA repair pathway, 32 genes from the growth hormone 1/ insulin-like growth factor 1/insulin (GH/IGF-1/INS) signalling pathway and 16 additional genes repeatedly considered as candidates for human longevity: APOE, APOA4, APOC3, ACE, CETP, HFE, IL6, IL6R,...
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