Article
Analyzing large-scale samples confirms the association between rs16892766 polymorphism and colorectal cancer susceptibility.
Scientific reports - 22 Jan 2015
Liao Mingzhi, Wang Guangyu, Quan Baoku, Qi Xingsi, Yu Zhihui, Feng Rennan, Zhang Liangcai, Jiang Yongshuai, Zhang Yanqiao, Liu Guiyou
Abstract excerpt
Colorectal cancer (CRC) is a common complex disease caused by the combination of genetic variants and environmental factors. Genome-wide association studies (GWAS) have been performed and reported some novel CRC susceptibility variants. The rs16892766 (8q23.3) polymorphism was first identified to be significantly associated with CRC in European ancestry. The following studies investigated this association in...
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