Article
Genome-Wide Expression Profiling and Phenotypic Analysis of Downstream Targets Identify the Fox Transcription Factor Jumeau as a Master Regulator of Cardiac Progenitor Cell Division.
International journal of molecular sciences - 1 Dec 2024
Hasan M Rezaul, Kump Andrew J, Stepaniak Evelyn C, Panta Manoj, Shashidhar Kuncha, Katariya Rajnandani, Sabbir Mofazzal K, Schwab Kristopher R, Inlow Mark H, Chen Ye, Ahmad Shaad M
Abstract excerpt
Forkhead box (Fox) transcription factors (TFs) mediate multiple conserved cardiogenic processes in both mammals and Drosophila. Our prior work identified the roles of two Drosophila Fox genes, jumeau (jumu) and Checkpoint suppressor 1-like (CHES-1-like), in cardiac progenitor cell specification and division, and in the proper positioning of cardiac cell subtypes. Fox TF binding sites are also significantly...
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