Article
A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos.
Proceedings of the National Academy of Sciences of the United States of America - 6 Jan 2004
Kim Yong-Ou, Park Sang-Joon, Balaban Robert S, Nirenberg Marshall, Kim Yongsok
Abstract excerpt
Identifying genetic components is an essential step toward understanding complex developmental processes. The primitive heart of the fruit fly, the dorsal vessel, which is a hemolymph-pumping organ, has provided a unique model system to identify cardiogenic genes and to further our understanding of the molecular mechanisms of cardiogenesis. Using RNA interference in developing Drosophila embryos, we performed a...
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