Article
The Association of IFNL4 Gene Polymorphisms with Hepatitis B Virus (HBV) Infection in the Northern Region of Pará, Brazil.
International journal of molecular sciences - 9 Oct 2024
Andrade Álesson Adam Fonseca, Angelim Carolina Cabral, Martins Letícia Dias, Sacramento Amanda Roberta Vieira, Sousa Renata Santos de, Correa Raissa Lima, Conde Simone Regina Souza da Silva, Vallinoto Antonio Carlos Rosário, Feitosa Rosimar Neris Martins, Costa Greice de Lemos Cardoso
Abstract excerpt
It is heavily suggested that one IFNL4 gene polymorphism, rs12979860 (T/C), exerts influence on the outcome of HBV infection, with the rs12979860-T allele being classified as a risk predictor, and the rs12979860-C allele being classified as a protective one. This study investigated whether the rs12979860 IFNL4 gene polymorphism presented any association with the clinical severity for HBV carriers in an admixed...