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Article

Investigating the causal association between branched-chain amino acids and Alzheimer's disease: A bidirectional Mendelian randomized study

31 Mar 2023

Abstract excerpt

Background There are many metabolic pathway abnormalities in Alzheimer's disease (AD). Several studies have linked branched-chain amino acid (BCAA) metabolism disorders with AD but have not obtained consistent results. The purpose of this study is to explore the causal association between BCAA concentration and the risk of AD. Methods A bidirectional Mendelian randomized (MR) study was applied to explore the...

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PMID: 37063328
DOI: 10.3389/fnut.2023.1103303

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