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Article

Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer’s disease

7 May 2021

Abstract excerpt

Neurodegenerative diseases like Alzheimer's, Parkinson's and Huntington's disease involves abnormal aggregation and accumulation of toxic proteins aggregates. Post-translational modifications (PTMs) of the causative proteins play an important role in the etiology of disease as they could either slow down or accelerate the disease progression. Alzheimer disease is associated with the aggregation and accumulation...

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PMID: 33962636
DOI: 10.1186/s12964-021-00732-z

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