Article
Routine next generation sequencing of lymphoid malignancies: clinical utility and challenges from a 3-Year practical experience.
Leukemia & lymphoma - 1 Nov 2020
Pillonel Vincent, Juskevicius Darius, Bihl Michel, Stenner Frank, Halter Jörg P, Dirnhofer Stefan, Tzankov Alexandar
Abstract excerpt
Since 2016, a next-generation sequencing (NGS) panel targeting 68 genes frequently mutated in lymphoid malignancies is an accredited part of routine diagnostics at the Institute of Pathology in Basel, Switzerland. Here, we retrospectively evaluate the feasibility and utility of integrating this NGS platform into routine practice on 80 diagnostic cases of lymphoid proliferations. NGS analysis was useful in most...
Topics
- High-Throughput Nucleotide Sequencing
- Humans
- Mutation
- Neoplasms
- Prognosis
- Retrospective Studies