Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

N‐Acetylcysteine Treats Spinal Cord Injury by Inhibiting Astrocyte Proliferation

1 Jan 2024

Abstract excerpt

Astrocyte proliferation commonly occurs after spinal cord injury (SCI). N‐Acetylcysteine (NAC) has a regulatory effect on many diseases. In this study, we investigated the effect and underlying mechanism of NAC on astrocytes in SCI. We isolated rat primary astrocytes and stimulated with lipopolysaccharide to induce cell proliferation and degeneration. A rat model of SCI was also established, and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nerve injury and regeneration
Share to Neurogenesis and neuroplasticity mechanisms
Share to Spinal Cord Injury Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39624161
DOI: 10.1155/2024/6624283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

N‐Acetylcysteine Treats Spinal Cord Injury by Inhibiting Astrocyte ProliferationPMID 39624161Read ↗

Understanding the Role of the Glial Scar through the Depletion of Glial Cells after Spinal Cord InjurySemantic proximity Read ↗

Role of astrocytes in the pathogenesis of perinatal brain injurySemantic proximity Read ↗

Astrogliosis.Semantic proximity Read ↗

GDF‐11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3‐Mediated Autophagy AugmentationSemantic proximity Read ↗

Glutamate Increases In Vitro Survival and Proliferation and Attenuates Oxidative Stress-Induced Cell Death in Adult Spinal Cord-Derived Neural Stem/Progenitor Cells via Non-NMDA Ionotropic Glutamate Receptors.Semantic proximity Read ↗

Ascorbic Acid Can Promote the Generation and Expansion of Neuroepithelial-Like Stem Cells Derived from HiPS/ES Cells Under Chemically Defined Conditions Through Promoting Collagen SynthesisSemantic proximity Read ↗

Signaling molecules regulating phenotypic conversions of astrocytes and glial scar formation in damaged nerve tissues.Semantic proximity Read ↗

Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.Semantic proximity Read ↗

The tri-culture system reveals an activation cascade from microglia through astrocytes to neurons during neuroinflammationSemantic proximity Read ↗

Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-κB/C3 Pathway.Semantic proximity Read ↗

SARM1 promotes neuroinflammation and inhibits neural regeneration after spinal cord injurySemantic proximity Read ↗

Inflammation Promotes a Conversion of Astrocytes into Neural Progenitor Cells via NF-κB Activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.