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Article

Signaling molecules regulating phenotypic conversions of astrocytes and glial scar formation in damaged nerve tissues.

Neurochemistry international - 1 Dec 2014

Koyama Yutaka

Abstract excerpt

Phenotypic conversion of astrocytes from resting to reactive (i.e., astrocytic activation) occurs in numerous brain disorders. Astrocytic activation in severely damaged brain regions often leads to glial scar formation. Because astrocytic activation and glial scar largely affect the vulnerability and tissue repair of damaged brain, numerous studies have been made to clarify mechanisms regulating the astrocytic...

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Source

Identifiers

PMID: 25180676
DOI: 10.1016/j.neuint.2014.08.005

Genes

OLIG2
STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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