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Article

Dose-dependent interferon programs in myeloid cells after mRNA and adenovirus COVID-19 vaccination

2025-08-18

Abstract excerpt

The SARS-CoV-2 pandemic provided a rare opportunity to study how human immune responses develop to a novel viral antigen delivered through different vaccine platforms. However, to date, no study has directly compared immune responses to all three FDA-approved COVID-19 vaccines at single-cell multi-omic resolution. We longitudinally profiled SARS-CoV-2–naïve adults (n=31) vaccinated with BNT162b2, mRNA-1273, or Ad2...

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Literature Corpus work
a57f3a93-4afa-57f4-9d65-d03c94956f2f
DOI
10.1101/2025.08.15.668720
Open publication

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Dose-dependent interferon programs in myeloid cells after mRNA and adenovirus COVID-19 vaccinationDOI 10.1101/2025.08.15.668720
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