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Article

[Association between cigarette smoking, genetic polymorphism and myelodysplasia: a multicentric case-control study].

Medicina clinica - 14 Mar 2025

de Las Heras Rodríguez Natalia, Megido Lahera Marta, González Porras José Ramón, Sánchez Campos Sonia, Díez Láiz Raquel, Fuertes Núñez Marta, Ramos Ortega Fernando

Abstract excerpt

BACKGROUND: Both cigarette smoking (CGS), through its role as a benzene source, and some metabolic detoxyfiying enzymes (EDTOX) polymorphisms that hamper its inactivation, are considered as risk factors for the development of myelodysplastic neoplasms (MDS) and related disorders. This study aims to confirm such associations. PATIENTS AND METHODS: We recruited 61 patients diagnosed with MDS following FAB Group...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NAD(P)H Dehydrogenase (Quinone)

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Source

Identifiers

PMID: 39613711
DOI: 10.1016/j.medcli.2024.09.017

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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